Sculptra vs Profhilo: Find Your Perfect Match

Choosing between anti-aging treatments can feel overwhelming, especially when both promise remarkable results. The Profhilo vs Sculptra debate is common among those considering skin rejuvenation in Thailand, and the answer isn’t one-size-fits-all. Profhilo excels at hydration and skin quality, while Sculptra focuses on collagen stimulation and volume restoration. Some patients even combine both treatments for comprehensive rejuvenation. Understanding how each works will help you make the right choice for your skin goals.

What Are Profhilo and Sculptra?

Profhilo

Profhilo is a hyaluronic acid-based injectable that works differently from traditional dermal fillers. Instead of adding volume to specific areas, it spreads beneath the skin to hydrate deeply and improve overall skin quality. The treatment:

Boosts skin hydration from within
Enhances elasticity and firmness
Stimulates natural collagen and elastin production
Creates a natural glow and healthier-looking skin

Sculptra

Sculptra in Bangkok has gained popularity as a powerful collagen stimulator. At our aesthetic clinic in Bangkok, we use this FDA-approved poly-L-lactic acid injectable to help patients achieve long-lasting rejuvenation. The treatment:

Stimulates your body’s natural collagen production
Gradually restores lost facial volume
Addresses deep wrinkles and facial sagging
Delivers results that can last up to two years

Profhilo vs. Sculptra – Which One Is Right For You?

Understanding the differences between these treatments helps you determine which aligns with your goals:

Treatment Focus

Profhilo: Primarily targets hydration, skin texture, and firmness
Sculptra: Focuses on collagen production and volumizing

Results Timeline

Profhilo: Results visible within 2-4 weeks after treatment
Sculptra: Gradual improvement over 3-6 months as collagen builds

Longevity

Profhilo: Results typically last 6-9 months
Sculptra: Effects can last up to two years

Treatment Areas

Profhilo: Face, neck, décolletage, and hands
Sculptra: Face (especially temples, cheeks, and jawline)

Number of Sessions

Profhilo: Usually requires 2 initial treatments
Sculptra: Typically needs 3 sessions for optimal results

combining Sculptra and Profhilo for best results at Nirunda Clinic Bangkok

Can You Combine Sculptra and Profhilo?

Can you combine Sculptra and Profhilo? Absolutely. Many of our patients at Nirunda Clinic benefit from using both treatments together. This combination approach offers comprehensive rejuvenation:

Sculptra rebuilds the skin’s structural foundation by boosting collagen and restoring volume
Profhilo enhances skin quality, hydration, and surface texture

This dual-treatment strategy addresses both volume loss and skin quality simultaneously, delivering more complete results. During your consultation at our clinic, our board-certified aesthetic doctors will evaluate your skin condition and recommend a personalized treatment plan that may include one or both options.

Which Treatment Is Better?

Is Profhilo or Sculptra better? The answer depends entirely on your individual concerns and aesthetic goals.

Choose Profhilo if you want to:

Improve skin hydration and achieve a healthy glow
Address mild skin laxity and crepiness
Enhance overall skin quality and texture
Target fine lines caused by dehydration
See faster initial results

Choose Sculptra if you want to:

Restore significant volume loss in the face
Address deep wrinkles and folds (nasolabial lines, marionette lines)
Treat moderate-to-severe facial sagging
Achieve longer-lasting results (up to two years)
Gradually build a more youthful facial structure

Some patients start with one treatment and later add the other, while others opt for both from the beginning. It is important to consult with experienced professionals who can assess your unique needs.

Why Choose Our Aesthetic Clinic in Bangkok?

At Nirunda, one of the best aesthetic clinics in Bangkok, we offer both Profhilo and Sculptra treatments administered by experienced, board-certified aesthetic doctors. Here’s what sets us apart:

Expertise and Certification

Our doctors are accredited and certified to administer both treatments
We source Sculptra directly from the authorized distributor, Galderma Thailand
Years of experience in delivering natural-looking results

Personalized Approach

Thorough consultations to understand your goals
Customized treatment plans tailored to your skin type and concerns
Honest recommendations about which treatment—or combination—will work best

State-of-the-Art Facility

Advanced technology and modern equipment
Safe, comfortable environment
High standards of patient care and hygiene

Natural-Looking Results

Focus on enhancing your natural beauty
Gradual transformations that don’t look “overdone”
Comprehensive post-treatment care and guidance

Time For A New You

Both Profhilo and Sculptra are highly effective treatments for skin rejuvenation, each with unique benefits. The best choice depends on your specific concerns, desired timeline, and aesthetic goals. Some patients find that combining both treatments delivers the most comprehensive results.

At our Bangkok clinic, we’re committed to helping you make informed decisions about your skin. Our expert team will evaluate your skin condition, discuss your expectations, and create a personalized treatment plan designed to help you look and feel your best.

Time to start your rejuvenation journey with Nirunda Clinic. Schedule a consultation with us today to explore how Profhilo, Sculptra, or a combination of both can help you achieve beautiful, natural-looking results.

References:

The Cosmetic Skin Clinic. (2023, November 16). Sculptra vs Profhilo. Retrieved November 17, 2025, from https://www.cosmeticskinclinic.com/blog/sculptra-vs-profhilo/
Dobbie, V. (2024, December 19). Profhilo® vs Sculptra®: How do they compare? DRVICTORIA™. Retrieved November 17, 2025, from https://drvictoria.co.uk/blog/profhilo-vs-sculptra
Al‑Ayoubi, A. (2025, September 26). Is Sculptra or Profhilo better? Treatment comparison. LMA Clinic. Retrieved November 17, 2025, from https://www.lmaclinic.com/lma/blog/is-sculptra-or-profhilo-better