Profhilo vs Juvelook vs Rejuran vs Sculptra: Which Is Best?

People seeking fresher, smoother, and more youthful skin without surgery often opt for injectable rejuvenation treatments. These treatments can address dryness, early sagging, texture issues, pore size, and volume loss. With growing interest in skin rejuvenation in Thailand, four names consistently stand out: Juvelook, Profhilo, Rejuran, and Sculptra. Each one works differently, so understanding their benefits makes it easier to choose the option that fits your skin concerns.

Whether you want hydration, healing, collagen stimulation, or volume restoration, there is a targeted treatment designed for each need.

Overview of Juvelook, Profhilo, Rejuran, and Sculptra

Juvelook

Juvelook is a hybrid formula made from polylactic acid (PLA) and hyaluronic acid. It is often selected for acne scars, enlarged pores, and dull skin. The PLA stimulates collagen, while hyaluronic acid adds light hydration. Results appear gradually and downtime is minimal.

Profhilo

Profhilo contains highly concentrated hyaluronic acid, which spreads evenly beneath the skin to boost moisture and improve elasticity. It is helpful for dryness, crepey skin, early sagging, and fine lines. Common treatment areas include the face, neck, and hands.

Rejuran

Rejuran Healer uses polynucleotides derived from salmon DNA. It repairs sensitive or weakened skin, strengthens the skin barrier, refines texture, and calms inflammation. It is often used on the entire face, the under-eye area, and acne-scarred skin.

Sculptra

Sculptra works differently from skin boosters. It contains poly-L-lactic acid (PLLA) and focuses on deeper tissue support. Instead of hydrating the skin’s surface, it restores facial volume and gradually stimulates collagen. This is why Sculptra is commonly chosen for hollow cheeks, temples, and deeper folds.

Profhilo vs Juvelook vs Rejuran: What Makes Them Different?

These three treatments are considered skin boosters, but each targets specific concerns. Here is a simple comparison:

Profhilo: Best for hydration, glow, and mild lifting.
Juvelook: Best for texture improvement, pore refinement, and light collagen support.
Rejuran: Best for repairing sensitive, damaged, or aging skin.

They also vary in injection depth, recovery time, and how quickly results appear. Your choice depends on whether hydration, texture refinement, or skin repair is your main priority.

When to Consider Sculptra Instead of Skin Boosters

Skin boosters improve moisture, texture, and general skin quality. Sculptra, however, is ideal for people who need deeper rejuvenation such as:

Restoring facial volume
Lifting sunken or hollow areas
Supporting long-term collagen production

Some patients combine Sculptra with skin boosters to improve both structure and surface texture.

Can You Do Juvelook and Profhilo Together?

Yes. Juvelook and Profhilo can complement each other because they address different concerns. Juvelook works on texture and collagen stimulation, while Profhilo improves hydration and elasticity. Combined, they can make skin look smoother, firmer, and more radiant.

Combination plans must be spaced properly, and the timing is always evaluated by an aesthetic doctor.

Can You Combine Profhilo and Rejuran?

Yes. These two treatments are often combined for patients who want both moisture and skin healing. Rejuran strengthens and repairs the skin, while Profhilo improves suppleness and glow. Proper spacing between sessions ensures comfort and optimal results.

Can Sculptra Be Combined With Other Treatments?

Yes. Sculptra can be paired with skin boosters, but scheduling is important because it works at a deeper level. A trained aesthetic doctor will design the appropriate treatment timeline to avoid overstimulating the skin.

Skin booster session for woman who evaluated Profhilo vs Juvelook vs Rejuran for her needs

How to Choose the Right Treatment

NAD+ therapy offers a supportive way to replenish a molecule that your body relies on for energy production, cellular repair, and metabolic balance. If you want to enhance your energy, improve mental clarity, or support overall vitality, finding a medically supervised IV drip in Thailand is a proactive step toward better health.

To learn more or schedule a consultation, contact Nirunda Clinic today and explore how NAD+ therapy can support your wellness goals.

Reference:

7 Major Benefits of NAD+ IV Therapy. Retrieved November 24, 2025, from https://ivboost.uk/7-major-benefits-of-nad-iv-therapy/?srsltid=AfmBOoqdZGquPVTWBr2w9-NwcqfGG8jtg0xt1DsPFRmUQEM55wktWIMu

What is NAD+ IV Drip? and What Benefits Does it Offer? Retrieved November 24, 2025, from https://www.novomed.com/nad-iv-drip-cellular-therapy-for-boosted-energy-levels/