Everyday life exposes our skin to stress – from pollution and UV rays to lack of sleep and constant screen time. Over time, these factors can lead to dullness, fine lines, and loss of elasticity. The good news? Modern aesthetic medicine has made it possible to restore skin vitality without surgery.
At Nirunda Clinic in Bangkok, one of Thailand’s leading centers for advanced aesthetic treatments, we specialize in working with your skin’s natural processes. Among our most popular treatments is the Rejuran skin booster, an innovative therapy that’s transforming how people approach skin rejuvenation. Unlike temporary fixes, Rejuran treatment works at a cellular level to genuinely improve your skin’s health and appearance from within.

So, what is Rejuran exactly? It’s a question many of our patients ask, and the answer is both simple and fascinating. Rejuran injection therapy uses polynucleotides (PN), which are biocompatible DNA fragments extracted from wild salmon. Before you worry – these molecules are highly purified and processed to be completely safe for human use.
Think of polynucleotides as messengers that communicate with your skin cells, encouraging them to repair and regenerate naturally. The salmon DNA used in Rejuran is remarkably compatible with human skin, sharing about 97% similarity, which is why it’s so effective at triggering your body’s own healing mechanisms without causing adverse reactions.
This Rejuran skin booster has gained tremendous popularity throughout Asia and beyond because it offers something unique: genuine skin improvement rather than just surface-level enhancement.
Understanding how Rejuran treatment works helps explain why it delivers such impressive results. When polynucleotides are injected into your skin’s deeper layers, they get to work immediately:
Unlike fillers, Rejuran injections don’t add volume. Instead, it focuses on healing and restoring the skin’s structure for a soft, natural glow.
The Rejuran skin booster is incredibly versatile, making it suitable for a wide range of people. You might be an ideal candidate if you:
That said, there are some contraindications. You should avoid Rejuran treatment if you have a salmon allergy, are pregnant or breastfeeding, are taking blood thinners, or have active skin infections in the treatment area. During your consultation at Nirunda Clinic, our specialists will assess your skin and medical history to ensure Rejuran is the right choice for you.
The Rejuran healer benefits work far beyond simple wrinkle reduction. This comprehensive treatment offers multiple advantages:
Long-Term Skin Health: Unlike treatments that provide temporary results, Rejuran injection therapy improves your skin’s fundamental structure and function, creating benefits that extend well beyond the treatment period.
Deep Hydration: Rejuran attracts and locks moisture into your skin, creating that coveted plump, dewy appearance. Well-hydrated skin naturally looks younger and healthier.
Improved Texture and Tone: By encouraging cellular renewal, the Rejuran skin booster refines rough patches and creates a smoother, more even complexion. Many patients notice their skin feels softer within just a few weeks.
Fine Line and Wrinkle Reduction: Increased collagen production naturally plumps the skin from within, softening the appearance of fine lines and wrinkles for a more youthful look.
Enhanced Elasticity and Firmness: As collagen and elastin levels increase, skin becomes firmer and more resilient, with improved bounce and elasticity.
Accelerated Healing: The treatment’s regenerative properties make it excellent for addressing acne scars, sun damage, and other forms of skin trauma. The anti-inflammatory effects support faster, clearer healing.
Understanding what happens during your Rejuran treatment helps you feel prepared and comfortable. Here’s what to expect at Nirunda Clinic:
Your journey begins with a thorough consultation with one of our board-certified aesthetic specialists. We’ll examine your skin, discuss your concerns and goals, and create a personalized treatment plan.
On treatment day, we’ll cleanse your skin thoroughly and apply a topical numbing cream to ensure your comfort. This sits for about 20-30 minutes before the procedure begins.
Using ultra-fine needles, our skilled practitioners perform a series of micro-injections across the treatment area. The Rejuran injection technique involves creating multiple small punctures that allow precise delivery of the solution into your skin’s dermal layer. The entire process typically takes 30-60 minutes, depending on the areas being treated.
Right after treatment, you may notice small raised bumps where each injection was administered – these look somewhat like tiny mosquito bites. This is completely normal and part of the process.
At Nirunda Clinic, we use advanced injection techniques and state-of-the-art facilities to ensure optimal results with maximum patient comfort. Our internationally accredited specialists have extensive experience with Rejuran treatment, giving you confidence that you’re in expert hands.
One of the most attractive aspects of Rejuran injection therapy is the minimal downtime. Here’s what your recovery typically looks like:
Looking at Rejuran before and after photos from our patients, the improvements are clear – smoother texture, more even tone, reduced fine lines, and an overall more youthful, radiant appearance.

Both exosome and Rejuran skin booster treatments are popular non-invasive options for skin rejuvenation, but they work differently:
Exosome Therapy delivers growth factors and regenerative components that accelerate healing and cellular communication. It’s particularly powerful for rapid regeneration and can show faster initial results.
Rejuran Treatment focuses on deep hydration, collagen stimulation, and structural skin repair through its polynucleotide-based formula. It’s especially noted for anti-inflammatory properties and its ability to strengthen the skin barrier.
While both treatments effectively enhance skin quality, Rejuran injection stands out for:
Many patients at Nirunda Clinic find that Rejuran treatment offers a more comprehensive approach to skin health, addressing multiple concerns simultaneously. However, during your consultation, our specialists can help determine which treatment, or combination of treatments, best suits your specific needs.
Selecting the right clinic for your Rejuran treatment is crucial to achieving safe, effective results. Here’s why Nirunda Clinic stands out:
Our board-certified doctors and aesthetic specialists maintain international accreditation and stay current with the latest advances in aesthetic medicine.
We invest in cutting-edge medical technology and maintain the highest standards of safety and hygiene, ensuring every treatment is performed with precision and care.
We recognize that every patient is unique. Rather than one-size-fits-all solutions, we create customized treatment plans tailored to your specific skin concerns and aesthetic goals.
From your initial consultation through post-treatment follow-up, we provide continuous support to ensure you’re completely satisfied with your results.
Our numerous positive patient testimonials and impressive before-and-after results speak to our commitment to excellence. When you look at Rejuran before and after images from our patients, you’ll see the quality of care we provide.
Choosing between treatments can feel overwhelming. Our specialists take the time to explain the Rejuran healer benefits and help you understand how this treatment compares to other options, ensuring you make an informed decision.
At Nirunda Clinic in Bangkok, we’re not just treating skin; we’re helping people feel confident and beautiful in their own skin.
If you’re seeking a natural, effective solution for youthful, revitalized skin, the Rejuran skin booster might be exactly what you’ve been looking for. This innovative Rejuran treatment offers comprehensive benefits that improve not just how your skin looks, but how it functions at a fundamental level.
Don’t settle for tired, aging skin when genuine rejuvenation is within reach. Contact Nirunda Clinic today to schedule your consultation. Our team of experts is ready to answer your questions, address your concerns, and guide you toward achieving the radiant, healthy skin you deserve.
Book Your Consultation Now and take the first step toward a more youthful, confident you.
A: Yes, Rejuran injection uses polynucleotides extracted from wild salmon DNA. The salmon DNA is highly purified and processed, making it approximately 97% compatible with human DNA. It’s been extensively researched and is considered very safe. However, if you have a salmon allergy, you should not receive this treatment.
A: Most patients begin noticing improvements within 1-2 weeks after their first session, with more dramatic results appearing at 3-4 weeks. Optimal results typically manifest around 4-6 weeks post-treatment when collagen production reaches its peak. Results continue to improve with each subsequent session in your treatment series.
A: The Rejuran treatment involves multiple micro-injections, which can feel uncomfortable, but most patients describe it as tolerable rather than painful. At Nirunda Clinic, we apply a topical numbing cream before treatment to minimize discomfort. We also use ultra-fine 30-34 gauge needles and advanced injection techniques to ensure maximum comfort.
A: The effects of Rejuran injection typically last 6-12 months, depending on factors like your age, lifestyle, skin condition, and how well you care for your skin post-treatment. To maintain optimal results, we recommend maintenance treatments every 6-12 months after completing your initial series.
A: For optimal results, we recommend an initial series of 3-4 Rejuran treatment sessions spaced 3-4 weeks apart. This allows the benefits to build progressively. Some patients with significant skin concerns may benefit from additional sessions. Your Nirunda specialist will create a personalized plan based on your specific needs.
A: No, Rejuran injection is not a dermal filler. Fillers add volume to specific areas, while Rejuran works at a cellular level to improve overall skin quality, texture, and health. Think of it as a skin quality enhancer rather than a volumizer. Interestingly, many patients combine Rejuran with fillers for comprehensive facial rejuvenation.
A: Yes! The Rejuran skin booster is highly versatile and often combined with treatments like Botox, dermal fillers, laser treatments, HIFU, or other procedures. In fact, Rejuran can enhance the effectiveness of other treatments and support faster recovery after more invasive procedures. Your Nirunda specialist will help create an optimal combination treatment plan.
A: Rejuran treatment has minimal side effects. Immediately after treatment, you may experience temporary redness, mild swelling, and small raised bumps at injection sites – these typically resolve within 12-48 hours. Some patients experience minor bruising. Serious side effects are rare when the treatment is performed by qualified professionals.
A: Yes, most patients resume normal activities, including work, immediately after their Rejuran injection session. While you’ll have small raised bumps visible for several hours, these typically subside within 12-24 hours. We recommend avoiding heavy makeup for the first 24 hours and staying out of direct sun.
A: Different Rejuran treatment formulations target specific concerns: Rejuran Healer is the standard formulation for overall facial rejuvenation; Rejuran I is specially designed for delicate eye area treatment; Rejuran S is formulated for targeted scar treatment; and Rejuran HB contains lidocaine for enhanced comfort. Your Nirunda specialist will recommend the best formulation for your needs.